I have fixed the issue where ADB over USB no longer works after the OTA3 ICS upgrade, on my Windows 7 X64 system. Go to C:\users\"User Name"\.android\adb_usb.ini and open adb_usb.ini in wordpad and simply add "0x17EF" without the quotation marks to the first empty line, then save and exit and all of the adb commands will work. I had seen a reference to this in the ADB installation topic but there were no complete instructions, so it took me a bit to figure it out.
Edit: You will need to have install SDK in order to have adb_usb.ini for modification. The guide for installing is in our forum Here.